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Reason: Under embargo until 30 June 2024. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library.
Novel Therapeutics for the Treatment of Stroke
thesisposted on 2023-06-13, 22:34 authored by ADRIANA KNEZIC
Despite the incidence and devastating consequences of stroke, there are relatively few treatments for stroke victims. To address this unmet need, we assessed two potential new drugs, C21 and Hi1a, to evaluate whether they could be protective against stroke. In order to do this, we optimised a pre-clinical animal model of stroke. Unfortunately, C21 had limited effects in the context of stroke. However, excitingly, using a clinically relevant model of stroke and method of drug delivery, we found that Hi1a minimised sensory- and weight-loss caused by stroke. This highlights Hi1a as a potential drug candidate for the application of stroke.