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Reason: Under embargo until September 2019. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Novel Compounds for Anti-Cancer Directed Enzyme Prodrug Therapy Utilising Nitroreductase

thesis
posted on 2018-09-06, 04:35 authored by ANDREW TANG
Cancer is a disease with global impact and there is a constant need to develop new treatments to target it. One method is to take potent drugs and activate them at the tumour. We’ve been working on a strategy that will release potent drugs only when activated by a specific enzyme which can be delivered to the tumour. We have success designed a chemical system that only releases the payload in the presence of the enzyme. We hope that this design will be used to make anti-cancer drugs safer.

History

Campus location

Australia

Principal supervisor

Jonathan Baell

Year of Award

2018

Department, School or Centre

Medicinal Chemistry

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Pharmacy and Pharmaceutical Sciences

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    Faculty of Pharmacy and Pharmaceutical Sciences Theses

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