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New materials for cancer imaging and therapy

thesis
posted on 12.03.2018 by ROBBIN RALF VERNOOIJ
The increasing burden of cancer on society drives the development of more effective chemotherapeutic agents. The work in this thesis is therefore centred on the examination of a new series of metal-based anticancer prodrug candidates. These metal-based compounds do not exhibit toxicity in the dark, but can be activated with light in cancerous areas, avoiding unwanted side-effects in healthy tissues. A range of state-of-the- art spectroscopic techniques, including vibrational spectroscopy and synchrotron radiation, are applied to study the chemical and biological properties of these compounds, revealing new insights into their mechanism of action.

History

Campus location

Australia

Principal supervisor

Bayden Wood

Additional supervisor 1

Prof. Peter J. Sadler

Additional supervisor 2

Prof. Vasilios G. Stavros

Year of Award

2018

Department, School or Centre

Chemistry

Additional Institution or Organisation

University of Warwick

Course

Doctor of Philosophy (Joint award with the University of Warwick)

Degree Type

DOCTORATE

Faculty

Faculty of Science

Exports