Monash University
Browse

Neuronal Control of Distal Mitochondrial Stress Responses and Their Impact on Metabolism

Download (23.46 MB)
thesis
posted on 2024-04-03, 02:30 authored by REBECCA JADE CORNELL
Life is stressful, and so the ability to respond appropriately to physiological stress is an essential skill for all living organisms. This thesis examines the mechanisms the brain uses to control mitochondrial health in the rest of the body. The results presented in this thesis describe two novel molecular pathways which originate in the nervous system and impact intestinal mitochondrial health. These results may have interesting implications for disease states where neuronal communication is disrupted – for example, during neurodegenerative diseases – which have metabolic impacts on various body systems.

History

Principal supervisor

Roger David John Pocock

Additional supervisor 1

Ava Handley

Year of Award

2024

Department, School or Centre

Anatomy and Developmental Biology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

Usage metrics

    Faculty of Medicine, Nursing and Health Sciences Theses

    Categories

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC