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Multiomics dissection of Chikungunya virus pathogenesis reveals Neuropilin 2 as a novel therapeutic target

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thesis
posted on 2023-05-08, 02:39 authored by NUR AMELIA AZREEN ADNAN
Chikungunya virus (CHIKV) can infect humans via Aedes mosquito bites and causes joint pain, fever, rashes and sometimes death in immunocompromised patients. Currently, there are no approved antivirals or vaccines for CHIKV. This thesis covers the pathogenesis of CHIKV in human muscle cells as well as the road to unveil the therapeutics target that can be used to reduce the CHIKV infection severity.

History

Principal supervisor

Vinod Balasubramaniam

Additional supervisor 1

Ammu Kutty Radakrishnan

Additional supervisor 2

Amreeta Dhanoa

Additional supervisor 3

Tham Hong Wai

Year of Award

2023

Department, School or Centre

Jeffrey Cheah School of Medicine and Health Sciences (Monash University Malaysia)

Campus location

Malaysia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

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    Faculty of Medicine, Nursing and Health Sciences Theses

    Categories

    Keywords

    Chikungunya virusAlphavirusNeuropilin 2host-virus interactionantiviralyeast two-hybridRNAseq

    Licence

    In Copyright

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