Monash University
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Molecular mechanisms that generate muscle fibre type diversity during vertebrate evolution

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thesis
posted on 2020-08-04, 08:24 authored by SAMUEL RHYS KEENAN
Identification and characterisation of what genes are required for developing specific muscle cells in 3D axes. I identify a novel gene pathway involved in this process, which is required for activating formation of the muscle cell of interest. I also uncover the adult fates and functions of these muscle cells. These gene pathways operate on one small DNA region, which I then investigate individual DNA binding sites and its functional evolution.

History

Principal supervisor

Peter Currie

Additional supervisor 1

Mirana Ramialison

Additional supervisor 2

Frank Tulenko

Year of Award

2020

Department, School or Centre

Australian Regenerative Medicine Institute (ARMI)

Additional Institution or Organisation

ARMI

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences