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Reason: Under embargo until November 2018. After this date a copy can be supplied under Section 51 (2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library
Molecular insights into lipid-based antigen recognition by Natural Killer T cell antigen receptors
Version 2 2019-06-12, 22:45
Version 1 2017-11-20, 22:44
thesisposted on 2019-06-12, 22:45 authored by SRINIVASAN SUNDARARAJ
Our body comprises a group of defense warriors that protect us from the infections caused by microbes such as bacteria and viruses. These soldiers typically sense the proteins present in microbes to execute their functions. Recently, a special group of defense warriors was identified which senses fats from microorganisms for their protective function. In this PhD thesis, the structural basis underpinning how these specialized warriors recognize microbial fats and its influence on the outcome of numerous medical conditions have been examined.