PhD Thesis_Alice Berizzi_comments addressed.pdf (14.71 MB)

Modulation of Muscarinic Acetylcholine Receptors in Ethanol-seeking Behaviours

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posted on 24.06.2018, 04:24 by ALICE ESTHER BERIZZI
The M5 muscarinic receptor is a protein that can regulate the compulsive use of abused drugs, including cocaine and morphine, and therefore has emerged as an interesting drug target for the treatment of alcohol use disorders. Until recently, drugs that selectively target the M5 muscarinic receptor have been lacking. This thesis sought to identify and understand how selective drugs for the M5 muscarinic receptor act and their utility in models of alcohol use disorders.


Campus location


Principal supervisor

Christopher Langmead

Additional supervisor 1

Arthur Christopoulos

Additional supervisor 2

Andrew Lawrence

Year of Award


Department, School or Centre

Drug Discovery Biology

Additional Institution or Organisation

Monash Pharmacy and Pharmaceutical Sciences


Doctor of Philosophy

Degree Type



Faculty of Pharmacy and Pharmaceutical Sciences