Modulation of Muscarinic Acetylcholine Receptors in Ethanol-seeking Behaviours
thesisposted on 24.06.2018 by ALICE ESTHER BERIZZI
In order to distinguish essays and pre-prints from academic theses, we have a separate category. These are often much longer text based documents than a paper.
The M5 muscarinic receptor is a protein that can regulate the compulsive use of abused drugs, including cocaine and morphine, and therefore has emerged as an interesting drug target for the treatment of alcohol use disorders. Until recently, drugs that selectively target the M5 muscarinic receptor have been lacking. This thesis sought to identify and understand how selective drugs for the M5 muscarinic receptor act and their utility in models of alcohol use disorders.