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Minimally invasive placental MSC Based Cellular Therapy for Alleviation of Maternal Birth Injury

thesis
posted on 07.06.2021, 02:36 by MANIJEH KHANMOHAMMADI
A vaginal birth injury can progress to pelvic organ prolapse (POP), usually in menopausal women. Currently, there are no optimal procedures for preventing POP. Developing cells therapy for women who can use their own’s cells to repair the damaged tissue is vital. Hence, this study aimed to evaluate the effect of pMSCs delivered in the hydrogel in a rat model of acute birth injury. Animal study results indicated that treated injured vaginas appear to show a slight improvement. This treatment aims to prevent POP development, resulting in a reduction in the number of surgeries required for this condition.

History

Principal supervisor

Caroline Gargett

Additional supervisor 1

Shayanti.Mukherjee@hudson.org.au

Additional supervisor 2

fiona.cousins@hudson.org.au

Year of Award

2021

Department, School or Centre

Obstetrics and Gynaecology

Additional Institution or Organisation

The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australia

Campus location

Australia

Course

Master of Philosophy

Degree Type

MPHIL

Faculty

Faculty of Medicine, Nursing and Health Sciences

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