Monash University

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Reason: Under embargo until September 2019. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Mechanisms of accelerated atherosclerosis in rheumatoid arthritis

posted on 2018-09-18, 22:39 authored by DRAGANA DRAGOLJEVIC
Patients with rheumatoid arthritis (RA) are up to 3 times more likely to develop cardiovascular disease (CVD), resulting in premature death. What is alarming, however, is that patients don’t always present with traditional CV risk factors such as high cholesterol levels (dyslipidemia). My project highlights that augmented white blood cell (WBC) levels contribute to increased heart disease in RA, and therapies which can alter either the abundance or the behaviour of WBCs can reduce heart disease in the setting of RA. Furthermore, this may provide clinicians with a new parameter to consider when accessing CVD in RA patients.


Principal supervisor

Andrew Murphy

Year of Award


Department, School or Centre

Central Clinical School

Additional Institution or Organisation

Immunology - Alfred


Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences