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Mechanisms and Therapeutics of Heart Failure with Preserved Ejection Fraction

thesis
posted on 09.10.2019, 04:01 by SHANE SANJEEWA NANAYAKKARA
Heart failure is a condition where the heart’s function does not match the needs of the body. 50% of heart failure cases are due to HFpEF (heart failure with preserved ejection fraction), where there are no effective therapies due in part to a lack of understanding of the mechanisms. In this thesis we explore the underlying causes through detailed pre-clinical and clinical studies, extending to artificial intelligence, and concluding with the first randomised trial of a novel drug.

History

Principal supervisor

David Martin Kaye

Additional supervisor 1

Melissa Byrne

Year of Award

2019

Department, School or Centre

Central Clinical School

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences