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Lipidated polymers for stabilization and antibacterial applications

thesis
posted on 16.07.2019 by JAMES LYNDEN GRACE
This thesis investigates a series of novel lipidated low molecular weight polymer materials comprised of various lipid elements and macromolecular architecture for use as antimicrobials, or as stabilizers. It was found that careful selection of the length of the lipid tail and the polymer constituents played a strong role in the activity of the polymer against mammalian and microbial cells. The charge of the polymer was also found to affect the stabilization.

History

Campus location

Australia

Principal supervisor

Michael Raymond Whittaker

Additional supervisor 1

John F. Quinn

Additional supervisor 2

Nghia Truong

Additional supervisor 3

Thomas P. Davis

Year of Award

2019

Department, School or Centre

Drug Delivery, Disposition and Dynamics

Additional Institution or Organisation

ARC Centre of Excellence in Convergent Bio-Nano Science and Technology

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Pharmacy and Pharmaceutical Sciences

Exports

Exports