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Reason: Under embargo until October 2022. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library
L-asparaginase Produced from Endophytes: Production, Optimization and Anticancer Activities
thesis
posted on 2021-10-11, 01:02 authored by Ling Sze YapL-asparaginase is an anticancer drug used to treat acute lymphoblastic leukemia. The commercial available L-asparaginase derived from bacteria has reported to induce several life-threatening side effects and irreversible complications. This thesis examines the utilization of endophytic fungi isolated from medicinal plants as an alternative source of L-asparaginase. It demonstrates the ability of endophytic fungi to produce L-asparaginase, factors affecting L-asparaginase production, purification process and anticancer effect of fungal-derived L-asparaginase.
