Monash University
PhD Thesis Merriman Feb 22 2019.pdf (7.45 MB)

Isolated Distal Vein Deep Vein Thrombosis: Diagnosis and Management Strategies

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posted on 2019-06-11, 00:59 authored by EILEEN GRACE MERRIMAN
This multicentre prospective cohort study enrolled patients with isolated distal deep vein DVT in Australia and New Zealand. 140 (70%) were assigned to two weeks anticoagulation (asymptomatic; group C); 56 (28%) to group B (ongoing symptoms; 6 weeks anticoagulation); and three patients (2%) had proximal extension on 2-week ultrasound (group A). Two patients in the two-week anticoagulation arm had symptomatic distal DVT recurrence; VTE recurrence rate 3/131; 2.3% (95% CI 0.47-6.55%). There were no symptomatic proximal DVT/PE recurrences, no major bleeding episodes, and a low rate of mild PTS (4.3%, 95% CI 1.7-8.6%), with no episodes of severe PTS.


Principal supervisor

Huyen Tran

Year of Award


Department, School or Centre

Central Clinical School


Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences

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    Faculty of Medicine, Nursing and Health Sciences Theses