24529869_Zhe_Hao_Tan_PhD_Thesis Final with Amendments.pdf (48.63 MB)
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Investigations of the Endothelial Surface Layer and Monocyte Subsets in Glomerular Inflammation

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thesis
posted on 23.04.2021, 07:19 by ZHE HAO TAN
This thesis examined the role of the blood vessel surface layer and subsets of a specific type of white blood cell known as monocytes, in models of immune-mediated kidney inflammation. It was determined that the blood vessel surface layer plays a complex role in regulating the recruitment of various white blood cells. Additionally, an approach for imaging monocyte subsets was developed. Finally, it was revealed that two monocyte subsets can mediate inflammation in a model of immune-mediated kidney inflammation.

History

Principal supervisor

Michael Hickey

Additional supervisor 1

A. Richard Kitching

Additional supervisor 2

M. Ursula Norman

Year of Award

2021

Department, School or Centre

Medicine - Monash Health

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

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