24529869_Zhe_Hao_Tan_PhD_Thesis Final with Amendments.pdf (48.63 MB)
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Investigations of the Endothelial Surface Layer and Monocyte Subsets in Glomerular Inflammation

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posted on 2021-04-23, 07:19 authored by ZHE HAO TAN
This thesis examined the role of the blood vessel surface layer and subsets of a specific type of white blood cell known as monocytes, in models of immune-mediated kidney inflammation. It was determined that the blood vessel surface layer plays a complex role in regulating the recruitment of various white blood cells. Additionally, an approach for imaging monocyte subsets was developed. Finally, it was revealed that two monocyte subsets can mediate inflammation in a model of immune-mediated kidney inflammation.


Principal supervisor

Michael Hickey

Additional supervisor 1

A. Richard Kitching

Additional supervisor 2

M. Ursula Norman

Year of Award


Department, School or Centre

Medicine - Monash Health

Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine, Nursing and Health Sciences