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Investigating the function of MACPF proteins in development and growth using Drosophila melanogaster

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thesis
posted on 2019-04-03, 23:27 authored by MELISSA JANE SALIGARI
This thesis examines the developmental roles of perforin-like proteins, which are more commonly known for their role in immunity. This thesis also identifies two neuropeptide receptors as novel regulators of growth in Drosophila. Overall, this thesis demonstrates the diverse developmental roles of perforin-like proteins and highlights the effectiveness of using Drosophila as a model system to investigate gene function. This will deepen our understanding of an important protein family implicated in human development and disease.

History

Campus location

Australia

Principal supervisor

Coral G Warr

Additional supervisor 1

Travis K Johnson

Additional supervisor 2

Christen K Mirth

Year of Award

2018

Department, School or Centre

Biological Sciences

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Science

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