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Investigating the Utility of Lipid-Based Formulations for Ionic Liquid Drug Delivery
thesisposted on 2019-07-03, 09:29 authored by ERIN ING-PIN TAY
This thesis explores the potential for alternate salt forms of drugs to improve drug loading in lipid formulations used in capsules. The composition of the lipid formulation plays a key role in the bioavailability of the alternate salt form of the drug. Additionally, a larger, bulkier counter-ion that is paired with a drug will increase drug loading in lipid formulations. These alternate salt forms of drugs have higher drug loading in lipid formulations than the traditional salt forms and provide a potential means to increase the dose for some medications.