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Investigating the Therapeutic Potential of Extracellular Vesicles Derived From Gestational Cells For Perinatal Cerebral and Pulmonary Injury

thesis
posted on 2025-07-18, 04:19 authored by Naveen Kumar
Premature birth poses significant health risks for newborns, frequently leading to lung injury and brain damage. These complications increase the risk of developing bronchopulmonary dysplasia, a chronic lung disease, and cerebral palsy, a condition affecting movement and coordination. Despite medical advancements, the incidence of these conditions remains a persistent issue. My PhD research explored extracellular vesicles—small particles naturally released by cells from the amnion and umbilical cord—as a treatment to protect and heal the lungs and brain of preterm babies. In my research, we achieved encouraging outcomes in animal studies that establish a foundation for potential clinical investigation.<p></p>

History

Principal supervisor

Rebecca Lim

Additional supervisor 1

Tamara Yawno

Additional supervisor 2

Ishmael Inocencio

Additional supervisor 3

Dandan Zhu

Year of Award

2025

Department, School or Centre

Obstetrics and Gynaecology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

Rights Statement

The author retains copyright of this thesis. It must only be used for personal non-commercial research, education and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission. For further terms use the In Copyright link under the License field.

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