Monash University

Embargoed and Restricted Access

Reason: Under embargo until 31 July 2023. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library.

Investigating the Role of AIM2 in Lung Adenocarcinoma

posted on 2022-07-18, 01:12 authored by MOHAMMAD AHAMD A ALANAZI

Lung cancer is the most lethal cancer worldwide. There are no effective therapies to cure this disease due to some reasons, including severe side effects and drug resistance. Thus, there is an urgent need to investigate further the underlying mechanisms of lung cancer to develop effective therapies for lung cancer patients. This thesis has identified AIM2 (protein) to play a carcinogenic role in lung cancer. The carcinogenic role of AIM2 enhances our understanding of lung cancer and presents AIM2 as a key player in promoting lung cancer.


Principal supervisor

Brendan Jenkins

Year of Award


Department, School or Centre

Central Clinical School

Additional Institution or Organisation

Molecular and Translational Science (Hudson Institute)

Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine, Nursing and Health Sciences