Investigating Prostate Cancer Radiobiology and the Mechanisms of Response and Resistance to Radioligand Therapy

Everard, Isabel Mercedes

doi:10.26180/30585167.v1

Investigating Prostate Cancer Radiobiology and the Mechanisms of Response and Resistance to Radioligand Therapy

https://doi.org/10.26180/30585167

thesis

posted on 2025-11-18, 13:38 authored by Isabel Mercedes Everard

This research used patient-derived tumour models to investigate why some prostate cancers do not respond to the targeted radioligand therapy Lutetium-177-PSMA. It aimed to identify tumour-specific factors influencing treatment effectiveness and resistance, providing insights into how to optimise this therapy and improve outcomes for patients with advanced prostate cancer.

History

Principal supervisor

Gail Petuna Risbridger

Additional supervisor 1

Renea Taylor

Additional supervisor 2

Laura Porter

Additional supervisor 3

Natalie Lister

Year of Award

2025

Department, School or Centre

Anatomy and Developmental Biology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

Rights Statement

The author retains copyright of this thesis. It must only be used for personal non-commercial research, education and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission. For further terms use the In Copyright link under the License field.

Investigating Prostate Cancer Radiobiology and the Mechanisms of Response and Resistance to Radioligand Therapy

History

Principal supervisor

Additional supervisor 1

Additional supervisor 2

Additional supervisor 3

Year of Award

Department, School or Centre

Campus location

Course

Degree Type

Faculty

Rights Statement

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Categories

Keywords

Licence

Exports