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Interaction of polyphenols with the gut and digestive processes

thesis
posted on 2024-02-01, 04:43 authored by RIZLIYA VISVANATHAN
The gut plays a central role in determining how polyphenols (plant-derived compounds found in many foods and beverages) affect human health. This study investigates the effects of polyphenols in reducing the risk of type 2 diabetes and COVID-19, with an emphasis on the gut-mediated mechanisms of polyphenols. The findings indicate that polyphenols can slow starch digestion and glucose absorption in the gut, which could potentially lower post-meal blood glucose spikes, a major risk factor for type 2 diabetes in humans. Moreover, certain polyphenols decrease the SARS-CoV-2 viral entry receptors in gut cells, which may limit COVID-19 infection and progression.

History

Principal supervisor

Gary Williamson

Additional supervisor 1

Michael J Houghton

Additional supervisor 2

Elizabeth Barber

Year of Award

2024

Department, School or Centre

Nutrition and Dietetics

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

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    Faculty of Medicine, Nursing and Health Sciences Theses

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