Embargoed and Restricted Access

Reason: Under embargo until April 2020. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Injectable cell-laden microgels for regeneration of human articular cartilage tissue

thesis
posted on 11.04.2019, 00:09 authored by FANYI LI
This thesis reports a novel tissue engineering strategy using a facile, very low cost-based microfluidic technique to produce visible light crosslinked microgels composed of protein-based material for human articular cartilage tissue regeneration. By introducing a biocompatible bonding process, these protein-based microgels can be engineered into higher-order tissue like structure with additional ability for native tissue adhesion. This study demonstrates the superiority compared to conventional bulk hydrogel with encouraging potential of this system to be applied in the further cartilage tissue clinical translate studies, with additional potential for a broad range of regenerative medicine.

History

Campus location

Australia

Principal supervisor

John Stanley Forsythe

Additional supervisor 1

Jessica Ellen Frith

Additional supervisor 2

Helmut Thissen

Year of Award

2019

Department, School or Centre

Materials Science and Engineering

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Engineering