Monash University
Browse

Restricted Access

Reason: Access restricted by the author. A copy can be requested for private research and study by contacting your institution's library service. This copy cannot be republished

Improving targeted lipidomics to elucidate lipid pathways in Type 2 diabetes and Alzheimer’s disease

thesis
posted on 2018-12-20, 17:34 authored by KEVIN HUYNH
Lipids are a broad range of small molecules that are associated with nearly all biological processes. These important molecules have rapidly gained interest as the field has advanced in the past decade due to improvements to mass spectrometry and chromatographic technologies. In this thesis, we developed and improved our lipidomics platform to better examine these lipids and applied them to two Australian cohorts to explore their relationship with type 2 diabetes and Alzheimer's disease. This thesis details the relationship between the plasma lipidome and these diseases.

History

Principal supervisor

Peter

Additional supervisor 1

Brian Drew

Year of Award

2018

Department, School or Centre

Central Clinical School

Additional Institution or Organisation

Baker Heart and Diabetes Institute

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine Nursing and Health Sciences