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Identification and characterisation of novel peptide activators of neprilysin and endothelin-converting enzyme-1

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thesis
posted on 2022-02-08, 02:02 authored by NKUMBU LUWI SIKANYIKA
Alzheimer’s is a disease caused by a toxic chemical build-up in the brain. My thesis investigates a new molecule that can increase the brain’s natural ability to break down this chemical build-up. In the end, I discovered 2 versions of the molecule that are better than the original and that could help us find new ways to treat Alzheimer's disease.

History

Principal supervisor

Helena Parkington

Additional supervisor 1

Sanjaya Kuruppu

Additional supervisor 2

A. Ian Smith

Year of Award

2022

Department, School or Centre

Biomedical Sciences (Monash Biomedicine Discovery Institute)

Additional Institution or Organisation

Physiology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences