Thesis_TH_Amended Sep2022.pdf (13.34 MB)
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Homeostasis and Function of Virtual Memory CD8 T Cells During Ageing and Infection

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thesis
posted on 12.09.2022, 04:25 authored by Tabinda Hussain
This work describes how an immune cell population, that is very sensitive to the inflammtory signals produced during the infection and ageing process, is generated, maintained and functions through the life course. We found that these immune cells, called TVM cells, react to select infections and inflammatory signals and acquire improvement in function which can be of use in designing therapeutic strategies for cancer and persistent infections.

History

Principal supervisor

Nicole La Gruta

Additional supervisor 1

Kylie Quinn

Additional supervisor 2

Annah Hearps

Year of Award

2022

Department, School or Centre

Biochemistry and Molecular Biology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences