Kelly Louise Short PhD Final .pdf (25.33 MB)

Glucocorticoid regulation of lung and kidney organogenesis during mouse fetal development

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thesis
posted on 29.10.2020, 05:02 by KELLY LOUISE SHORT
My thesis investigated how hormones help the growth of a developing baby in utero before birth. My studies showed that a steroid hormone called cortisol controls a complex network of genes and pathways to mature the newborn babies’ lung and kidney. Currently strong synthetic steroid drugs are used to treat very preterm babies and these can sometimes have adverse effects on their development. The new pathways I discovered will aid in the development of new therapeutic drugs to treat very preterm birth with reduced side effects.

History

Principal supervisor

Timothy James Cole

Year of Award

2020

Department, School or Centre

Biochemistry and Molecular Biology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

Exports

Exports