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Failure to progress in labour: influence of BMI and maternal age

thesis
posted on 11.03.2021, 08:18 by E Arachchige Ranga Iroshanie Edirisinghe Siriwardhana
Would you believe that, in the face of all medical advances, we have only one drug to help women with poor labour contractions? Currently the only available option to overcome failed labour is caesarean delivery which can put the health of mothers and their offspring at risk of complications. The challenges in developing mother- and child-safe drugs have held scientists back for decades. It is high time for new approaches. Here we have taken the first steps to address this by identifying potential targets for developing drugs to produce strong contractions in the uterus that will promote successful vaginal delivery.

History

Principal supervisor

Helena Parkington

Additional supervisor 1

Harold Coleman

Additional supervisor 2

Shaun Brennecke

Additional supervisor 3

Penny Sheehan

Year of Award

2021

Department, School or Centre

Physiology

Additional Institution or Organisation

Maternal Fetal Medicine Pregnancy Research centre, Royal Women's Hospital, Melbourne, Victoria, Australia

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

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