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Experimental and Computational Modelling of Particle Transport and Deposition Process in Inhalers and Upper Respiratory Tracts

thesis
posted on 11.05.2021, 21:43 by Fen Huang
This project studies the in vivo - in vitro correlation in the field of dry powder inhalers. It identifies the effects of inhalation parameters, including airflow rate, particle characteristics, inhaler structure, mouth-throat geometrical factors and inhaler usages, on particle deposition pattern in extrathoracic region through in vitro and in silico approaches. It also proposes mathematical correlations which consider the intersubject variability and initial conditions of inhalers to predict aerosol deposition in upper respiratory tracts.

History

Campus location

Australia

Principal supervisor

Zongyan Zhou

Additional supervisor 1

Aibing Yu

Additional supervisor 2

Zhenbo Tong

Year of Award

2021

Department, School or Centre

Chemical Engineering

Additional Institution or Organisation

Southeast University

Course

Doctor of Philosophy (Joint PhD with Southeast University - International)

Degree Type

DOCTORATE

Faculty

Faculty of Engineering