Monash University

Embargoed and Restricted Access

Reason: Under embargo until May 2022. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Experimental and Computational Modelling of Particle Transport and Deposition Process in Inhalers and Upper Respiratory Tracts

posted on 2021-05-11, 21:43 authored by Fen Huang
This project studies the in vivo - in vitro correlation in the field of dry powder inhalers. It identifies the effects of inhalation parameters, including airflow rate, particle characteristics, inhaler structure, mouth-throat geometrical factors and inhaler usages, on particle deposition pattern in extrathoracic region through in vitro and in silico approaches. It also proposes mathematical correlations which consider the intersubject variability and initial conditions of inhalers to predict aerosol deposition in upper respiratory tracts.


Campus location


Principal supervisor

Zongyan Zhou

Additional supervisor 1

Aibing Yu

Additional supervisor 2

Zhenbo Tong

Year of Award


Department, School or Centre

Chemical & Biological Engineering

Additional Institution or Organisation

Chemical Engineering


Doctor of Philosophy (Joint PhD with Southeast University - International)

Degree Type



Faculty of Engineering