Engineering the Orientation of Nanobody on Surfaces

YONG, WENG KEN

doi:10.26180/5f3487ba0f625

Thesis amended exam.pdf (24.7 MB)

Engineering the Orientation of Nanobody on Surfaces

thesis

posted on 2020-08-13, 00:22 authored by WENG KEN YONG

This thesis examines the effects of engineering the orientation a targeting group on a drug delivery surface for tumour targeting. It enables delivery to cancer cells without harming healthy cells, so decreasing the risk of side effects.

History

Principal supervisor

Angus Johnston

Year of Award

2020

Department, School or Centre

Drug Delivery, Disposition and Dynamics

Course

Doctor of Philosophy

Degree Type

DOCTORATE

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Keywords

Drug delivery Nanoparticle targeting Nanobody Single domain antibody Non-natural amino acid Expanding the genetic code Targeting ligand orientation Protein engineering Pharmaceutical Sciences

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Engineering the Orientation of Nanobody on Surfaces

History

Principal supervisor

Year of Award

Department, School or Centre

Course

Degree Type

Usage metrics

Categories

Keywords

Licence

Exports