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Engineering adhesive proteins enhanced by self-assembling peptide and enzyme cross-linking

thesis
posted on 19.06.2017, 23:27 by JAMIE JOSEPH CASTILLO
Conventional adhesives efficiently work on dry surfaces but fail in the presence of water. Currently, there is a great need for adhesives in surgical procedures and underwater construction. Nature gives a hint on how to develop wet adhesives. Mussels survive harsh underwater conditions by secreting an adhesive which attaches to different surfaces. However, natural extraction was found uneconomical. Recombinant engineering approach is a promising alternative method for large-scale adhesive production. Unfortunately, recombinant adhesives face drawbacks such as low performance. This thesis aims to address these drawbacks by designing and synthesising recombinant adhesives, developing a bioproduction, and evaluating their performance.

History

Campus location

Australia

Principal supervisor

Lizhong He

Additional supervisor 1

Victoria Haritos

Year of Award

2017

Department, School or Centre

Chemical Engineering

Course

Master of Engineering Science (Research)

Degree Type

MASTERS

Faculty

Faculty of Engineering