Dietary interventions to reduce advanced glycation endproducts (AGEs)

Advanced glycation endproducts (AGEs) are formed naturally inside the body, and within processed foods which we absorb from our diet. Elevated AGE levels in the body may contribute to the development of chronic diseases. A cross-sectional study found that a variety of lifestyle factors are associated with increased levels of AGE accumulation in skin. A clinical trial was conducted to determine whether a dietary fibre supplement could reduce circulating AGE levels in adults at risk of type 2 diabetes. While there were no changes in AGE levels, fibre consumption reduced waist circumference, urine protein levels and increased HDL(good) cholesterol levels.