L263 NASRULLAH THESIS FINAL 1ST SEPTEMBER 2018_Redacted.pdf (49.83 MB)
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Developmental patterns behind mammalian tooth generation and evolution

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posted on 03.04.2019, 23:36 by QAMARIYA NASRULLAH
Mammals showcase great diversity in tooth shape and size, helping them eat a variety of foods. To make teeth functional, their formation needs to be precisely controlled. This thesis examines patterns of tooth size, shape and replacement, and the controls behind the final product. I found that wallabies have unusual tooth replacement, and that controlling tooth size can allow for eternal replacement of teeth. Within mice, tooth-tooth inhibition can constrain the final tooth shape, allowing teeth to grow more or less complex. This thesis reveals fundamental controls that determine tooth size, shape and number in mammals.


Campus location


Principal supervisor

Alistair Evans

Additional supervisor 1

Edwina McGlinn

Year of Award


Department, School or Centre

Biological Sciences


Doctor of Philosophy

Degree Type



Faculty of Science