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Development of Magneto-responsive Assemblies based on Iron Oxide Nanoparticle for Controlled Drug Delivery

thesis
posted on 2025-11-30, 11:11 authored by Chin Siew Sia
This study developed magnetic nanoparticles enclosed in liposomes that can carry and release cancer drugs in a controlled way. These liposomes were used as emulsion stabilizer and made into beads that protect the drug from stomach acid and release it slowly in the colon. When exposed to a magnetic field, the beads heat up and release the drug more effectively. Tested on 3D tumor models, this method showed promising results in improving colon cancer treatment while reducing side effects. It could lead to more precise and effective ways to deliver cancer drugs in the future.<p></p>

History

Campus location

Malaysia

Principal supervisor

Low Liang Ee

Additional supervisor 1

Tey Beng Ti

Additional supervisor 2

Chan Eng Seng

Year of Award

2025

Department, School or Centre

School of Engineering (Monash University Malaysia)

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Engineering

Rights Statement

The author retains copyright of this thesis. It must only be used for personal non-commercial research, education and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission. For further terms use the In Copyright link under the License field.

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