Final Thesis_Uttam Dutta - Zeljka Abaza.pdf (19.25 MB)

Development of Highly Regioselective Functionalizations of Arenes, Heteroarenes and Alkynes

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posted on 04.08.2020, 02:02 by Uttam Dutta
Innovation and implementation of science and technology are the key parameter to define the socio-economic background of a nation. In the realm of modern chemical science, complexity of the biologically active molecules and the underlying mechanistic intricacies fascinated the synthetic chemists over the centuries. Structurally C−H and C−C bonds are the fundamental backbone of organic molecules. Hence, the expansion of synthetic scope of organic chemistry is largely dependent on devising a suitable protocol in a simple and environmentally binging way. The work presented in this thesis, entitled as “Development of Highly Regioselective Functionalizations of Arenes, Heteroarenes and Alkynes” describes the regioselective functionalizations of C−H and C−C bonds. In one part, the reactions have been devised relying on radical based metal free approaches, on the other hand, to accomplish highly regioselective transformations, a prudent combinations of transition metals, ligands, oxidants and template have been designed. In this regard, an unprecedented selective distal arene-meta and para-C−H bond has been functionalized using a preinstalled director.


Principal supervisor

D. Maiti

Additional supervisor 1

David W. Lupton

Year of Award


Department, School or Centre

School of Chemistry

Additional Institution or Organisation



Faculty of Science