Monash University
Grant, LK. Thesis document_Post examination amendments.pdf (6.67 MB)

Developing biomarkers of alertness: Biological determinants of vulnerability to alertness failure and biomarkers of alertness state

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posted on 2018-07-17, 04:44 authored by LEILAH KRISTINE GRANT
Sleep and circadian disruption are increasingly prevalent in today’s 24-hour society, due to sleep disorders, shift work and pressures on our time. These challenges have a profound impact on our safety and health, including an increased risk of sleepiness-related accidents. These negative outcomes could be prevented, however, if we had tools to measure and predict alertness levels more accurately. This thesis therefore aimed to develop biomarkers of alertness. The ability to predict alertness and intervene before an alertness failure occurs could directly reduce the risk of accidents and injuries, and their associated costs, and improve safety, performance and productivity.


Principal supervisor

Clare Anderson

Additional supervisor 1

Steven Lockley

Additional supervisor 2

Shantha Rajaratnam

Year of Award


Department, School or Centre

Psychological Sciences

Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences