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Design of Novel Cyclic Peptidomimetics – Melanocortin Peptides as An Example

thesis
posted on 2024-02-28, 07:02 authored by WENXIAO YUE
This thesis describes the idea of cyclic peptide mimetic based drug design applying to the studies of a group of G-protein coupled receptors named melanocortin receptors. Highly potent and selective peptide ligands targeting different subclasses of melanocortin receptors have been discovered through this work, supporting their potential applications as therapeutic strategies for treating a wide variety of conditions including diabetes and skin melanoma.

History

Campus location

Australia

Principal supervisor

Philip Thompson

Additional supervisor 1

Colin Pouton

Year of Award

2024

Department, School or Centre

Medicinal Chemistry

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Pharmacy and Pharmaceutical Sciences