Monash University
Browse
FY_thesis.pdf (26.38 MB)

Deciphering epigenetic alterations in pre-leukemic stem cells during T cell acute lymphoblastic leukemia development

Download (26.38 MB)
thesis
posted on 2022-03-18, 21:23 authored by FENG YAN
This thesis examines the aberrations in immature and chemo-resistant leukemia cells that cause an aggressive type of leukemia. It identified the earliest targets directly driven by an oncogene, and a scoring system for patient risk stratification.

History

Principal supervisor

David John

Additional supervisor 1

Nick Wong

Additional supervisor 2

David Powell

Year of Award

2022

Department, School or Centre

Australian Centre for Blood Diseases

Additional Institution or Organisation

Clinical Haematology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

Usage metrics

    Faculty of Medicine, Nursing and Health Sciences Theses

    Categories

    Keywords

    Leukemia stem cellsDNA methylationChromation accessibilityCancerBioinformaticsHematologyEpigenetics (incl. Genome Methylation and Epigenomics)

    Licence

    In Copyright

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC