Monash University
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Data-driven computational frameworks for modelling RNA functional properties

thesis
posted on 2025-09-17, 03:45 authored by Yue Bi
This thesis develops computer-based methods to help scientists better understand RNA, a key molecule in our cells that controls gene activity. The research focuses on three important questions: where RNA goes in the cell, which microRNAs bind to which targets, and which RNAs interact with which proteins. Each method is carefully designed using advanced machine or deep learning techniques to address the unique challenges of its task. Tests on large-scale datasets show that the methods work accurately and reliably. These tools will support future research by providing new ways to explore the roles of RNA in gene regulation.

History

Principal supervisor

Jiangning Song

Additional supervisor 1

Geoff Webb

Additional supervisor 2

Chen Davidovich

Year of Award

2025

Department, School or Centre

Biochemistry and Molecular Biology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

Rights Statement

The author retains copyright of this thesis. It must only be used for personal non-commercial research, education and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission. For further terms use the In Copyright link under the License field.