Monash University
Browse

Embargoed and Restricted Access

Reason: Under embargo until February 2022. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

CppA: A putative major fimbrial protein and novel virulence factor for clostridial myonecrosis

thesis
posted on 2021-02-09, 06:57 authored by DANIELLE FRANCES D'SOUZA
Clostridium perfringens is a bacterium that causes a ‘flesh-eating disease’ known as clostridial myonecrosis, primarily by producing potent toxins. This thesis examines a novel surface protein, CppA, which was shown to be a novel non-toxin disease determinant. CppA was also shown to form fimbriae-like appendages on the cell and potentially contributes to disease by mediating colonisation of host tissues. Therefore, the research described in this thesis has contributed to the knowledge of non-toxin disease factors for clostridial myonecrosis.

History

Principal supervisor

Julian Rood

Additional supervisor 1

Xiaoyan Han

Year of Award

2021

Department, School or Centre

Biomedical Sciences (Monash Biomedicine Discovery Institute)

Additional Institution or Organisation

Microbiology

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

Usage metrics

    Faculty of Medicine, Nursing and Health Sciences Theses

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC