Copper and Gallium PET Imaging Agents for Applications in HIV and Cancer

Positron emission tomography (PET) is a sensitive nuclear imaging technique that can highlight physiological and biochemical processes in vivo. If we extend the current utility of PET, we can both diagnose disease earlier, and improve our understanding of disease evolution. This thesis represents an investigation into PET applications in HIV and cancer, with new targeting vectors, and with novel chemical scaffolds.