Concomitant Treatment of Tocotrienol Rich Fractions and Temozolomide in Glioblastoma Spheroids Palms a Significant Synergistic Potential
thesis
posted on 2025-01-23, 00:25authored byBrandon Wee Siang Phon
Glioblastoma is a brain tumour that is infamous for being a thorn on the side of clinicians, with current treatment avenues barely improving patients' survival. This thesis looked into the potential of utilising vitamin E analogues to supplement the effects of the standard chemotherapeutic drug - temozolomide. It firmly establishes the potential of vitamin E analogues as a suitable supplement to temozolomide as a future clinical option that will not break the bank for glioblastoma patients.
History
Principal supervisor
Muhamad Noor Alfarizal Kamarudin
Additional supervisor 1
Ammu Kutty Radhakrishnan
Additional supervisor 2
B Saatheeyavaane Bhuvanendran Pillai
Year of Award
2025
Department, School or Centre
Jeffrey Cheah School of Medicine and Health Sciences (Monash University Malaysia)