Monash University
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Coding Synthetic DNA for Nanopore Sequencing

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thesis
posted on 2025-01-06, 04:18 authored by Brendon Peter McBain
This thesis studies error-correction codes for making synthetic DNA robust to errors in nanopore DNA sequencers. The nanopore sequencer reads DNA by generating signals, but it cannot control the speed at which DNA moves through it, leading to noisy signals with random stretches. This noise makes it difficult to read data stored in DNA reliably. The coding efficiency of an idealised nanopore sequencer is studied, and efficient codes are studied to make DNA storage reliable and practical.

History

Campus location

Australia

Principal supervisor

Emanuele Viterbo

Additional supervisor 1

James Saunderson

Additional supervisor 2

Nick Owen

Year of Award

2025

Department, School or Centre

Electrical and Computer Systems Engineering

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Engineering

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