Monash University

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Reason: Under embargo until September 2018. After this date a copy can be supplied under Section 51 (2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Clostridium perfringens and avian necrotic enteritis; novel virulence factors

posted on 2020-10-27, 02:47 authored by CHRISTOPHER BEN WADE
Avian necrotic enteritis is both an animal welfare concern and a disease of economic importance to the poultry industry. The disease is caused by the bacteria Clostridium perfringens. How this pathogen causes disease has been poorly understood for many years. The work of this project has shed light on how the process of collagen adherence plays a vital role in the bacteria's ability to colonise the host as well as the impact of bacterially encoded proteases in the disease process. This work has contributed substantially to our understanding of the underlying mechanisms involved in this serious disease.


Principal supervisor

Julian Ian Rood

Additional supervisor 1

Robert Moore

Additional supervisor 2

Anthony Keyburn

Year of Award


Department, School or Centre

School of Biomedical Sciences (Monash Biomedicine Discovery Institute)

Additional Institution or Organisation


Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences

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    Faculty of Medicine, Nursing and Health Sciences Theses