Monash University
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Clinical and pathophysiological aspects of nonalcoholic fatty liver disease in bariatric surgery

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posted on 2019-06-12, 06:05 authored by GERALDINE JIA-PING OOI
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide. NAFLD is closely linked with obesity, and can progress to cirrhosis and liver failure. Despite its prevalence, there is a limited understanding of NAFLD in the context of obesity and bariatric surgery, with few guidelines on clinical management and limited understanding of its pathophysiology. Bariatric surgery presents an ideal platform for NAFLD research. This thesis addresses key knowledge gaps in a range of clinical and pathophysiological areas encompassing the full spectrum of NAFLD, with the primary aim of improving management of this pervasive disease in obesity.


Principal supervisor

Wendy Brown

Additional supervisor 1

Paul Burton

Additional supervisor 2

Stuart Roberts

Additional supervisor 3

William Kemp

Year of Award


Department, School or Centre

Central Clinical School

Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences