Reason: Restricted by author. A copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library or by emailing firstname.lastname@example.org
Chronic tinnitus - seeking new insights into an intractable medical and social problem
In order to distinguish essays and pre-prints from academic theses, we have a separate category. These are often much longer text based documents than a paper.
posted on 15.02.2017by Dixon, Ian Edward
The underlying cause of chronic tinnitus (Cl) has not yet been described and there is no
universally successful treatment at this time. Chronic tinnitus is a phantom sound that
sometimes causes significant distress. Spontaneous remission from CT is rare in adults but
not children. An association between tinnitus factors such as aging, hearing deficit and diabetes is unclear.
This research has sought a new explanation for CT through the examination of a wide
range of literature and the building an in-depth and broad understanding of hearing related
research and other aspects that could be relevant.
Initial experimentation with ear homeostasis using a variety of pressure devices did not
achieve significant lasting changes to hearing thresholds, so a study involving 110 adult
participants was conducted to test the hypothesis that apoptosis (a process of orderly cell
death in vivo) is elevated in people with chronic tinnitus.
Using tinnitus severity and handicap inventories, the taking of blood samples and
measurement of apoptosemia in blood samples using cytochrome C as the read-out, no
significant differences in apoptosemia between participant subgroups was detected.
Using auditory scene analysis (ASA) and the observations of typical tinnitus remission in
children, an ASA-model of chronic tinnitus onset and maintenance has been developed and
which matches well-known literature - including the reported ability of specialised sounds
to suppress tinnitus in adults with tinnitus - and that could help direct future research in