Monash University
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Chiral, Water-Soluble Poly(2,4-dialkyl-2-oxazoline)s As Next Generation Biocompatible Nanomaterials

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thesis
posted on 2024-03-08, 06:21 authored by DAVID KEITH PIZZI
Biocompatible polymers are increasingly becoming a part of the formulation of medicines. These polymers help therapeutics to be better adsorbed and distributed throughout the body, reducing side effects and the dose required. This thesis explores the use of a new type of polymer as a potential therapeutic carrier. We show that the polymers can be incorporated into a variety of promising structures, and we can easily modify its water solubility and chirality. We demonstrate that by adjusting these parameters we can further modulate the behaviour of the polymers in the body. This research will help to develop future medicines.

History

Campus location

Australia

Principal supervisor

Kristian Kempe

Additional supervisor 1

Kristofer Thurecht

Year of Award

2023

Department, School or Centre

Drug Delivery, Disposition and Dynamics

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Pharmacy and Pharmaceutical Sciences