Chemokine Recognition and Signalling by the Chemokine Receptor CCR1
thesisposted on 26.03.2018 by JULIE SANCHEZ
In order to distinguish essays and pre-prints from academic theses, we have a separate category. These are often much longer text based documents than a paper.
Upon injury or infection, our bodies defend themselves through inflammation. This process involves the recruitment of white blood cells into the affected tissues. White blood cell migration is controlled by proteins called chemokines, which interact with receptors on the surfaces of the white blood cells. This project investigated molecular details of chemokine:receptor interactions and new strategies to target chemokines using proteins produced naturally by ticks. The results of this project will help to guide future development of medicines for inflammatory diseases like multiple sclerosis, rheumatoid arthritis and asthma.