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Chemokine Recognition and Signalling by the Chemokine Receptor CCR1

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thesis
posted on 26.03.2018 by JULIE SANCHEZ
Upon injury or infection, our bodies defend themselves through inflammation. This process involves the recruitment of white blood cells into the affected tissues. White blood cell migration is controlled by proteins called chemokines, which interact with receptors on the surfaces of the white blood cells. This project investigated molecular details of chemokine:receptor interactions and new strategies to target chemokines using proteins produced naturally by ticks. The results of this project will help to guide future development of medicines for inflammatory diseases like multiple sclerosis, rheumatoid arthritis and asthma.

History

Principal supervisor

Martin Stone

Additional supervisor 1

Richard Payne

Year of Award

2018

Department, School or Centre

Biochemistry and Molecular Biology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine Nursing and Health Sciences

Exports

Exports