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Characterization of the small mitochondrial RNAs, and their role in the regulation of mito-nuclear interactions.
thesisposted on 15.06.2020 by Andrea Pozzi
In order to distinguish essays and pre-prints from academic theses, we have a separate category. These are often much longer text based documents than a paper.
In this thesis, we characterized a new class of small RNAs encoded within the mitochondrial genome. We present evidence that these small RNAs are involved in a process called RNA interference and that they are conserved across animals. We document evidence that the small mitochondrial RNAs are able to interact with nuclear mRNAs, thus suggesting that these RNAs can influence cell regulation and animal phenotypes.