L91 Nikolce Kocovski Thesis 2018 Final_Redacted.pdf (6.03 MB)
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Characterising the equine antibody response to snake venom

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posted on 13.03.2019, 22:13 authored by NIKOLCE KOCOVSKI
This thesis investigates the B cells involved in the production of antivenom antibodies in horses, with the aim of isolating and characterising antibodies capable of neutralising venom toxins. Applying immunology and molecular techniques used in other systems, there was progress in identifying equine B cells, isolating their unique antibody genes, and producing these antibodies. Altogether, this work acts as a stepping stone towards a greater understanding of the development of antivenom antibodies, and potentially towards an improved antivenom against snake venom.


Principal supervisor

David Tarlinton

Additional supervisor 1

Professor Andrew Lew

Additional supervisor 2

Associate Professor Steven Rockman

Year of Award


Department, School or Centre

Central Clinical School

Campus location



Master of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences