L91 Nikolce Kocovski Thesis 2018 Final_Redacted.pdf (6.03 MB)
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Characterising the equine antibody response to snake venom

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thesis
posted on 13.03.2019 by NIKOLCE KOCOVSKI
This thesis investigates the B cells involved in the production of antivenom antibodies in horses, with the aim of isolating and characterising antibodies capable of neutralising venom toxins. Applying immunology and molecular techniques used in other systems, there was progress in identifying equine B cells, isolating their unique antibody genes, and producing these antibodies. Altogether, this work acts as a stepping stone towards a greater understanding of the development of antivenom antibodies, and potentially towards an improved antivenom against snake venom.

History

Principal supervisor

David Tarlinton

Additional supervisor 1

Professor Andrew Lew

Additional supervisor 2

Associate Professor Steven Rockman

Year of Award

2018

Department, School or Centre

Central Clinical School

Campus location

Australia

Course

Master of Philosophy

Degree Type

MPHIL

Faculty

Faculty of Medicine Nursing and Health Sciences

Exports