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Characterising novel aspects of Plasmodium falciparum phosphorylation and pathogenesis

thesis
posted on 09.02.2020, 23:47 by ANNA ELIZABETH SEXTON
Malaria remains one of the greatest global health problems today. This thesis examined how malaria parasites make people sick by zooming in on the microscopic battlefield between human and parasite. It was discovered that two proteins, found only malaria parasites, appear to help the parasite evade the human immune system. It was also revealed that malaria parasites release factors into the blood which negatively impact the function of human red blood cells. Altogether, this work helps us to understand the remarkably unique biology of malaria parasites.

History

Campus location

Australia

Principal supervisor

Darren John Creek

Additional supervisor 1

Teresa Gil Carvalho

Additional supervisor 2

Christian Doerig

Year of Award

2020

Department, School or Centre

Drug Delivery, Disposition and Dynamics

Course

Doctor of Philosophy

Degree Type

DOCTORATE

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